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          "xact_id": "xact-007",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-008",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-009",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-010",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-002"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-011",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-012",
          "xcol_id": "xcol-002"
        },
        {
          "xact_id": "xact-013",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-014",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-015",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-016",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-017",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-018",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-019",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-019",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-019",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-019",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-019",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-020",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-022",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-023",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-024",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-025",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-025",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-015"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-002"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-003"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-004"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-005"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-007"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-011"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-012"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-013"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-014"
        },
        {
          "xact_id": "xact-030",
          "xcol_id": "xcol-015"
        }
      ],
      "occurrence_count": 1
    },
    {
      "xannot_id": "xannot-002",
      "annotation_type": "legend",
      "annotation_text": "Performed at this visit if patient is an insulin-dependent diabetic.",
      "display_markers": "T1:a",
      "source_occurrences": [
        {
          "table_num": 1,
          "marker": "a",
          "annotation_id": "annot-002"
        }
      ],
      "referenced_xacts": [
        "xact-021"
      ],
      "referenced_xcols": [],
      "referenced_props": [],
      "cell_references": [
        {
          "xact_id": "xact-021",
          "xcol_id": "xcol-001"
        }
      ],
      "occurrence_count": 1
    },
    {
      "xannot_id": "xannot-003",
      "annotation_type": "legend",
      "annotation_text": "Performed at this visit and via telephone interview 2 weeks following this visit.",
      "display_markers": "T1:b",
      "source_occurrences": [
        {
          "table_num": 1,
          "marker": "b",
          "annotation_id": "annot-003"
        }
      ],
      "referenced_xacts": [
        "xact-029"
      ],
      "referenced_xcols": [],
      "referenced_props": [],
      "cell_references": [
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-008"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-009"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-010"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-011"
        }
      ],
      "occurrence_count": 1
    },
    {
      "xannot_id": "xannot-004",
      "annotation_type": "legend",
      "annotation_text": "Practice only - It is recommended that a sampling of the CIBIC+, ADAS-Cog, DAD, and NPI-X be administered at Visit 1. Data from this sampling would not be considered as study data and would not be collected.",
      "display_markers": "T1:P",
      "source_occurrences": [
        {
          "table_num": 1,
          "marker": "P",
          "annotation_id": "annot-004"
        }
      ],
      "referenced_xacts": [
        "xact-026",
        "xact-027",
        "xact-028",
        "xact-029"
      ],
      "referenced_xcols": [],
      "referenced_props": [],
      "cell_references": [
        {
          "xact_id": "xact-026",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-027",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-028",
          "xcol_id": "xcol-001"
        },
        {
          "xact_id": "xact-029",
          "xcol_id": "xcol-001"
        }
      ],
      "occurrence_count": 1
    }
  ],
  "review_items": [
    {
      "table_number": 1,
      "id": "D1",
      "severity": "high",
      "location": {
        "page": 53,
        "row_positions": [
          24,
          25,
          26
        ]
      },
      "call_made": "'Study drug record', 'Medications dispensed' and 'Medications returned' are printed as three lines inside ONE rule-bounded row cell with a single X per visit column (printed on the first line). Extracted as three activities, each carrying the same X at visits 3, 4, 5, 7, 8, 9, 10, 11, 12, 13 and ET (the cell's mark applies to every label in the cell).",
      "alternative": "Either (a) marks belong only to 'Study drug record' (the line the X is printed on) and 'Medications dispensed'/'Medications returned' carry no marks, or (b) the cell is a single activity 'Study drug record' whose extra lines are sub-items/descriptions rather than separate activities.",
      "report_section": "3.2"
    },
    {
      "table_number": 1,
      "id": "D2",
      "severity": "medium",
      "location": {
        "page": 53,
        "column_position": 8
      },
      "call_made": "The physical column between Visit 5 (week 4) and Visit 7 (week 6) on page 53, which has empty VISIT and WEEK header cells and no marks in any row, is kept as data column 8 with empty values.",
      "alternative": "Drop the empty column entirely (treat it as a presentation artefact, e.g. a deleted Visit 6), renumbering nothing else; or label it as an implied Visit 6 (not printed in the source).",
      "report_section": "3.3"
    },
    {
      "table_number": 1,
      "id": "D3",
      "severity": "low",
      "location": {
        "page": 54,
        "column_position": 16,
        "annotation_marker": "ab1"
      },
      "call_made": "Abbreviations ET (Early Termination) and RT (Retrieval) are kept as abbreviation annotations bound to the VISIT header cells that consist of exactly those terms (columns 16 and 17); CT and ECG from the same abbreviation line are dropped because they only occur inside activity labels.",
      "alternative": "Drop ET/RT as well (treat the whole abbreviation line as a standalone list with no in-grid marker), or keep CT/ECG bound to the 'CT Scan', 'ECG' and 'Ambulatory ECG' activity labels.",
      "report_section": "3.4"
    }
  ]
}