{
  "schema_name": "soa-table-extraction",
  "schema_version": "1.0",
  "extraction_metadata": {
    "extracted_at": "2026-09-27T13:08:13+00:00",
    "extractor": "Claude, PDF_TO_JSON_PROMPT single-pass",
    "prompt_version": "3.8.1",
    "source_document": {
      "filename": "NCT03693430_soa.pdf",
      "document_type": "protocol",
      "document_version": "3.0",
      "document_date": "29 June 2018"
    },
    "extraction_status": "ready_for_resolution",
    "extraction_notes": "Image-only PDF (each page a single 150-ppi raster, no text layer, no vector rules). Rule lines recovered from the raster (vertical rules by column ink fraction, horizontal rules by row ink fraction > 85%); marks detected by near-black pixel counts (<90) per cell (empty cells 0, marks 28-56) and validated against visual reads of every row. All text visually transcribed. Header rows reprinted on pages 10-12 de-duplicated. One label column (L=1); data columns 2-35 = V1..V34. Trial NN9536-4378.",
    "model": "claude-opus-5-5"
  },
  "table_metadata": {
    "table_number": 1,
    "table_type": "main_soa",
    "table_title": "Flowchart",
    "table_purpose": "Main schedule of activities: screening, randomisation, dose escalation, maintenance, end of treatment and end of trial",
    "page_start": 9,
    "page_end": 12,
    "notes": "Single printed table (\"2 Flowchart\") running over document pages 9-12 under a reprinted header; one table, not continuations. Page 11 and 12 each open with one activity row printed above the reprinted Visit/Timing/Window rows."
  },
  "schedule_properties": [
    {
      "table_number": 1,
      "row_position": 1,
      "property_name": "Period",
      "property_name_source": {
        "row_position": 1,
        "column_position": 1,
        "cell_value": "",
        "synthesized": true
      },
      "property_type": "epoch",
      "hierarchical_level": 1,
      "structure_method": "inferred_from_layout",
      "property_comment": "Top header band (label cell empty): study periods Screening (V1), Randomisation (V2), Dose escalation period (P3-V10, merged), Maintenance period (P11-V32, merged), End of treatment (V33), End of trial (V34). Typed epoch because the values name study phases; name synthesised. Merge extents taken from raster vertical-rule gaps."
    },
    {
      "table_number": 1,
      "row_position": 2,
      "property_name": "Visit (V), Phone(P)",
      "property_name_source": {
        "row_position": 2,
        "column_position": 1,
        "cell_value": "Visit (V), Phone(P)"
      },
      "property_type": "visit",
      "hierarchical_level": 2,
      "property_comment": "Visit identifiers V1-V34; prefix V = site visit, P = phone contact (per the row label). Unique per column, so typed visit."
    },
    {
      "table_number": 1,
      "row_position": 3,
      "property_name": "Timing of Visit (Weeks)",
      "property_name_source": {
        "row_position": 3,
        "column_position": 1,
        "cell_value": "Timing of Visit (Weeks)"
      },
      "property_type": "week",
      "hierarchical_level": 3,
      "property_comment": "Planned visit timing in weeks relative to randomisation (-1 to 111). Label printed \"Timing of visit (Weeks)\" (lower-case v) on the page-12 reprint. Typed week."
    },
    {
      "table_number": 1,
      "row_position": 4,
      "property_name": "Visit Window (Days)",
      "property_name_source": {
        "row_position": 4,
        "column_position": 1,
        "cell_value": "Visit Window (Days)"
      },
      "property_type": "window",
      "hierarchical_level": null,
      "property_comment": "Allowed visit window in days (-7 to 0, 0, ±3, 0 to +5). Typed window; hierarchical_level null because it does not distinguish any column from another. V33 prints ±3 on pages 9-10 but ±5 on the page 11-12 reprints; ±3 (first print) recorded, see review item D1."
    }
  ],
  "schedule_grid": [
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      "table_number": 1,
      "row_position": 1,
      "column_position": 2,
      "cell_value": "Screening",
      "method": "visual_read"
    },
    {
      "table_number": 1,
      "row_position": 1,
      "column_position": 3,
      "cell_value": "Randomisation",
      "method": "visual_read"
    },
    {
      "table_number": 1,
      "row_position": 1,
      "column_position": 4,
      "cell_value": "Dose escalation period",
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      "is_merged_cell": true,
      "merged_cell_range": "4:11"
    },
    {
      "table_number": 1,
      "row_position": 1,
      "column_position": 5,
      "cell_value": "Dose escalation period",
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      "merged_cell_range": "4:11"
    },
    {
      "table_number": 1,
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      "merged_cell_range": "4:11"
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    {
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    },
    {
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      "merged_cell_range": "4:11"
    },
    {
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    },
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    },
    {
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      "merged_cell_range": "4:11"
    },
    {
      "table_number": 1,
      "row_position": 1,
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      "cell_value": "Maintenance period",
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    },
    {
      "table_number": 1,
      "row_position": 1,
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    {
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    },
    {
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    },
    {
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    },
    {
      "table_number": 1,
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      "method": "visual_read"
    },
    {
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      "column_position": 35,
      "cell_value": "End of trial",
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    },
    {
      "table_number": 1,
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    {
      "table_number": 1,
      "row_position": 3,
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    {
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    {
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      "table_number": 1,
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      "table_number": 1,
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