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  "resolution_metadata": {
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    "resolver": "soa2usdm.steps.resolve v1.0",
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      "extraction_file": "NCT04184622_Table_01_extraction.verified.json",
      "extraction_status": "ready_for_resolution"
    },
    "validation_results": {
      "structure_valid": true,
      "hierarchy_valid": true,
      "annotations_valid": true,
      "validation_warnings": [],
      "validation_errors": [],
      "method_provenance": [
        "indentation_level:visual_estimate: 54",
        "marker_location:text_match: 35",
        "property_structure:inferred_from_layout: 2"
      ]
    },
    "resolution_status": "resolved",
    "ready_for_integration": true,
    "resolution_notes": ""
  },
  "extraction_metadata": {
    "extracted_at": "2026-09-27T12:58:17+00:00",
    "extractor": "Claude, PDF_TO_JSON_PROMPT single-pass",
    "prompt_version": "3.8.1",
    "source_document": {
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      "document_type": "protocol",
      "document_version": "I8F-MC-GPHK(b)"
    },
    "extraction_status": "ready_for_resolution",
    "extraction_notes": "All printed '*' markers in this table point to the 'Additional Information Regarding Activities Described in Schedule of Activities' table printed after Table 2 (document pages 25-28), per the source note '*Please see table below for corresponding additional information'. Because every marker prints as the same '*', each Additional Information note was given a synthesized id (n1..n27, identical across Tables 1 and 2) and bound to the starred element whose label matches that note's Activity cell (method text_match). The Additional Information table itself is not emitted as a table (its rows key to SoA elements; soa_table_type_definitions 'reference' rule). Abbreviation lists dropped (no in-grid abbreviation markers). Grid read by pdftotext -bbox column binning to Visit-row centres; row bands from raster rule lines.",
    "model": "claude-opus-5-5"
  },
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    "table_number": 1,
    "table_type": "main_soa",
    "table_title": "Schedule of Activities covering visits to primary study endpoint",
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    "page_start": 18,
    "page_end": 21,
    "track_label": null,
    "column_count": 24,
    "row_count": 59,
    "header_row_count": 5,
    "activity_row_count": 54,
    "notes": ""
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        "column_position": 1,
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      },
      "property_type": "visit",
      "property_comment": "Visit identifiers (1–21, 99, ED, 801 in Table 1; 101–116, 199, ED, 802 in Table 2); a named/numbered visit per column, so property_type visit. Uniquely identifies every column.",
      "hierarchical_level": 1,
      "parent_property_id": null,
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      "annotation_markers": "n1",
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        "column_position": 1,
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      },
      "property_type": "week",
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      "annotation_markers": "",
      "linked_annotation_ids": []
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      "table_id": "table-001",
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      "property_name": "Allowable Deviation (days)",
      "property_name_source": {
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        "column_position": 1,
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      },
      "property_type": "window",
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      "hierarchical_level": null,
      "parent_property_id": null,
      "child_property_ids": [],
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    {
      "annotation_id": "annot-025",
      "table_id": "table-001",
      "annotation_marker": "n25",
      "annotation_type": "footnote",
      "annotation_text": "PK samples will be collected at these visits at time windows of 1 to 24 hours, 24 to 96 hours, or 120 to 168 hours post dose, as assigned by IWRS at randomization. Dependent on the time windows to which a participant is assigned, they may be required to come to site for PK-specific visits.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-041"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 46,
          "method": "text_match"
        }
      ]
    },
    {
      "annotation_id": "annot-026",
      "table_id": "table-001",
      "annotation_marker": "n26",
      "annotation_type": "footnote",
      "annotation_text": "The C-SSRS, Self-Harm Supplement Form and PHQ-9 should be administered after assessment of adverse events. For this study, the C-SSRS is adapted for the assessment of the ideation and behavior categories only. The Intensity of Ideation and Lethality of Behavior sections are removed.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-045",
          "act-046",
          "act-047",
          "act-048"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 50,
          "method": "text_match"
        },
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 51,
          "method": "text_match"
        },
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 52,
          "method": "text_match"
        },
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 53,
          "method": "text_match"
        }
      ]
    },
    {
      "annotation_id": "annot-027",
      "table_id": "table-001",
      "annotation_marker": "n27",
      "annotation_type": "footnote",
      "annotation_text": "Self-Harm Follow-up Form is only required if triggered by the Self-Harm Supplement Form, per instructions in the form.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-049"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 54,
          "method": "text_match"
        }
      ]
    }
  ],
  "review_items": [
    {
      "id": "D1",
      "severity": "high",
      "location": {
        "page": 18,
        "row_position": 1,
        "annotation_marker": "n1"
      },
      "call_made": "Every '*' in the table was treated as pointing to one specific note of the 'Additional Information' table (pages 25-28): each note got its own id (n1-n27) and was attached to the starred row, visit or cell whose name matches that note's Activity cell.",
      "alternative": "Treat '*' as a single generic pointer ('see table below') and emit one annotation bound to every starred element, leaving the note-to-element matching to a later step.",
      "report_section": "3.1"
    },
    {
      "id": "D2",
      "severity": "high",
      "location": {
        "page": 19,
        "row_position": 25,
        "column_position": 22,
        "annotation_marker": "n16"
      },
      "call_made": "The note 'Dispense study drug Visit 72' (only for participants continuing into the prediabetes 2-year period) is attached only to the starred X of Dispense study drug at Visit 21 (Week 72), the one cell printed 'X*'.",
      "alternative": "Attach the note to the whole Dispense study drug row (all visits), since the note's own label names 'Visit 72', which does not exist as a visit number.",
      "report_section": "3.2"
    },
    {
      "id": "D3",
      "severity": "high",
      "location": {
        "page": 20,
        "row_positions": [
          38,
          39,
          40,
          41,
          44
        ],
        "column_position": 2,
        "annotation_marker": "n22"
      },
      "call_made": "The eligibility note for Urinary albumin/creatinine, Cystatin-c, Calcitonin, Hematology and TSH ('Screening visit assessment will be used to confirm eligibility ...') is attached only to their starred Visit 1 cells, where the '*' is printed.",
      "alternative": "Attach it to the five activity rows as a whole (all visits), and also to the same-named rows of Table 2 which carry no '*'.",
      "report_section": "3.2"
    },
    {
      "id": "D4",
      "severity": "medium",
      "location": {
        "page": 18,
        "row_positions": [
          4,
          5
        ]
      },
      "call_made": "'Fasting Visit' and 'Telephone Visit' (blue-shaded header rows reprinted on every page) are recorded as header properties (Fasting = other, Telephone = modality), not as activities.",
      "alternative": "Record them as activity rows with X marks at the fasting / telephone visits.",
      "report_section": "3.3"
    },
    {
      "id": "D5",
      "severity": "medium",
      "location": {
        "page": 21,
        "row_position": 51
      },
      "call_made": "The activity name is transcribed literally as printed: 'C-SSRS (Baseline/Screening) Version)', including the stray parenthesis.",
      "alternative": "Normalise to 'C-SSRS (Baseline/Screening Version)', the spelling used in the Additional Information table.",
      "report_section": "3.4"
    }
  ]
}