{
  "schema_name": "soa-table-resolved",
  "schema_version": "1.2",
  "resolution_metadata": {
    "resolved_at": "2026-10-03T15:51:01.567318+00:00",
    "resolver": "soa2usdm.steps.resolve v1.0",
    "source_extraction": {
      "schema_name": "soa-table-extraction",
      "schema_version": "1.0",
      "extraction_file": "NCT04573309_Table_01_extraction.verified.json",
      "extraction_status": "ready_for_resolution"
    },
    "validation_results": {
      "structure_valid": true,
      "hierarchy_valid": true,
      "annotations_valid": true,
      "validation_warnings": [],
      "validation_errors": [],
      "method_provenance": [
        "indentation_level:font_signal: 44",
        "marker_location:synthesized: 1",
        "property_structure:inferred_from_layout: 2",
        "schedule_cell:raster_pixel_detection: 40"
      ]
    },
    "resolution_status": "resolved",
    "ready_for_integration": true,
    "resolution_notes": ""
  },
  "extraction_metadata": {
    "extracted_at": "2026-09-27T13:08:28Z",
    "extractor": "Claude, PDF_TO_JSON_PROMPT single-pass",
    "prompt_version": "3.8.1",
    "source_document": {
      "filename": "NCT04573309_soa.pdf",
      "document_type": "amendment",
      "document_version": "Protocol Amendment 3.1 (US), ALXN1840-WD-204",
      "document_date": "18 Mar 2022"
    },
    "extraction_status": "ready_for_resolution",
    "extraction_notes": "Text-layer PDF with vector rule lines. Grid marks verified by pdftotext -bbox column binning against the rule-line column boundaries recovered from a 200 dpi raster; arrows measured from the raster.",
    "model": "claude-opus-5-5"
  },
  "table_metadata": {
    "table_id": "table-001",
    "table_number": 1,
    "table_type": "main_soa",
    "table_title": "Table 1: Schedule of Activities",
    "table_purpose": "Main study schedule from Screening through EOS/ET (Day 54+/-2), including both inpatient periods and the outpatient interval",
    "page_start": 14,
    "page_end": 16,
    "track_label": null,
    "column_count": 24,
    "row_count": 47,
    "header_row_count": 3,
    "activity_row_count": 44,
    "notes": "One printed table running over pages 14-15 with the header reprinted on page 15 (de-duplicated); footnotes a-h on page 15 and i-x on page 16; page 16 has no activity rows. One label column (L=1); data columns 2-25 (24 columns: 22 day columns, UNS, EOS/ET). Abbreviations block not emitted as annotations (no term used as a marker)."
  },
  "schedule_properties": [
    {
      "property_id": "prop-001",
      "table_id": "table-001",
      "row_position": 1,
      "property_name": "Study Phase",
      "property_name_source": {
        "row_position": 1,
        "column_position": 1,
        "cell_value": "",
        "synthesized": true
      },
      "property_type": "epoch",
      "property_comment": "Top header band: 'Screening' (Days -42 to -9 and -21), 'C-I' (check-in, Day -8), a blank merged cell over Days -7 to 40, 'UNS' (unscheduled) and 'EOS or ET'. The label column for rows 1-2 is a single merged cell reading 'Study Procedures' (the activity-column heading), so the property name is synthesised. Typed epoch because the values name study phases/visit categories spanning columns; distinguishes the UNS column (whose Days cell is empty) from the others.",
      "hierarchical_level": 1,
      "parent_property_id": null,
      "child_property_ids": [
        "prop-002"
      ],
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "property_id": "prop-002",
      "table_id": "table-001",
      "row_position": 2,
      "property_name": "Period",
      "property_name_source": {
        "row_position": 2,
        "column_position": 1,
        "cell_value": "",
        "synthesized": true
      },
      "property_type": "period",
      "property_comment": "Second header band: 'Screening', 'C-I', 'Inpatient Period 1' (merged over Days -7 to 9), 'OP' (outpatient, Days 10-22), blank at Day 23, 'Inpatient Period 2' (merged over Days 24 to 40), blank under UNS and EOS/ET. Sub-phases of the treatment phase -> period. Label cell is part of the merged 'Study Procedures' cell, so name synthesised.",
      "hierarchical_level": 2,
      "parent_property_id": "prop-001",
      "child_property_ids": [
        "prop-003"
      ],
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "property_id": "prop-003",
      "table_id": "table-001",
      "row_position": 3,
      "property_name": "Days",
      "property_name_source": {
        "row_position": 3,
        "column_position": 1,
        "cell_value": "Days"
      },
      "property_type": "study_day",
      "property_comment": "Study days / day ranges relative to first ALXN1840 dose (Day 1): -42 to -9 ... 40, blank under UNS, and 'EOS Day 54+/-2'. Printed label 'Days' -> study_day.",
      "hierarchical_level": 3,
      "parent_property_id": "prop-002",
      "child_property_ids": [],
      "annotation_markers": "",
      "linked_annotation_ids": []
    }
  ],
  "schedule_columns": [
    {
      "column_id": "col-002",
      "table_id": "table-001",
      "column_position": 2,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "Screening",
          "is_merged": true,
          "annotation_markers": "a"
        },
        {
          "property_id": "prop-002",
          "value": "Screening",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-42 to -9",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Screening / Screening / -42 to -9",
      "linked_annotation_ids": [
        "annot-001"
      ]
    },
    {
      "column_id": "col-003",
      "table_id": "table-001",
      "column_position": 3,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "Screening",
          "is_merged": true,
          "annotation_markers": "a"
        },
        {
          "property_id": "prop-002",
          "value": "Screening",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-21",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Screening / Screening / -21",
      "linked_annotation_ids": [
        "annot-001"
      ]
    },
    {
      "column_id": "col-004",
      "table_id": "table-001",
      "column_position": 4,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "C-I",
          "is_merged": false,
          "annotation_markers": "b"
        },
        {
          "property_id": "prop-002",
          "value": "C-I",
          "is_merged": false,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-8",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "C-I / C-I / -8",
      "linked_annotation_ids": [
        "annot-002"
      ]
    },
    {
      "column_id": "col-005",
      "table_id": "table-001",
      "column_position": 5,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-7",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / -7",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-006",
      "table_id": "table-001",
      "column_position": 6,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-6 through -5",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / -6 through -5",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-007",
      "table_id": "table-001",
      "column_position": 7,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "-4 through -1",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / -4 through -1",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-008",
      "table_id": "table-001",
      "column_position": 8,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "1",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / 1",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-009",
      "table_id": "table-001",
      "column_position": 9,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "2-3",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / 2-3",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-010",
      "table_id": "table-001",
      "column_position": 10,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "4-7",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / 4-7",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-011",
      "table_id": "table-001",
      "column_position": 11,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "8",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / 8",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-012",
      "table_id": "table-001",
      "column_position": 12,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 1",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "9",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 1 / 9",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-013",
      "table_id": "table-001",
      "column_position": 13,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "OP",
          "is_merged": false,
          "annotation_markers": "c"
        },
        {
          "property_id": "prop-003",
          "value": "10-22",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "OP / 10-22",
      "linked_annotation_ids": [
        "annot-003"
      ]
    },
    {
      "column_id": "col-014",
      "table_id": "table-001",
      "column_position": 14,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "",
          "is_merged": false,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "23",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "23",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-015",
      "table_id": "table-001",
      "column_position": 15,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "24",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 24",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-016",
      "table_id": "table-001",
      "column_position": 16,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "25",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 25",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-017",
      "table_id": "table-001",
      "column_position": 17,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "26-28",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 26-28",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-018",
      "table_id": "table-001",
      "column_position": 18,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "29",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 29",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-019",
      "table_id": "table-001",
      "column_position": 19,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "30-35",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 30-35",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-020",
      "table_id": "table-001",
      "column_position": 20,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "36",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 36",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-021",
      "table_id": "table-001",
      "column_position": 21,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "37-38",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 37-38",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-022",
      "table_id": "table-001",
      "column_position": 22,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "39",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 39",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-023",
      "table_id": "table-001",
      "column_position": 23,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-002",
          "value": "Inpatient Period 2",
          "is_merged": true,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "40",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "Inpatient Period 2 / 40",
      "linked_annotation_ids": []
    },
    {
      "column_id": "col-024",
      "table_id": "table-001",
      "column_position": 24,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "UNS",
          "is_merged": false,
          "annotation_markers": "d"
        },
        {
          "property_id": "prop-002",
          "value": "",
          "is_merged": false,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "UNS",
      "linked_annotation_ids": [
        "annot-004"
      ]
    },
    {
      "column_id": "col-025",
      "table_id": "table-001",
      "column_position": 25,
      "is_label_column": false,
      "column_values": [
        {
          "property_id": "prop-001",
          "value": "EOS or ET",
          "is_merged": false,
          "annotation_markers": "e"
        },
        {
          "property_id": "prop-002",
          "value": "",
          "is_merged": false,
          "annotation_markers": ""
        },
        {
          "property_id": "prop-003",
          "value": "EOS Day 54+/-2",
          "is_merged": false,
          "annotation_markers": ""
        }
      ],
      "composite_label": "EOS or ET / EOS Day 54+/-2",
      "linked_annotation_ids": [
        "annot-005"
      ]
    }
  ],
  "activities": [
    {
      "activity_id": "act-001",
      "table_id": "table-001",
      "row_position": 4,
      "activity_name": "Eligibility",
      "activity_name_source": {
        "cell_text": "Eligibility",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-002",
        "act-003",
        "act-004",
        "act-005",
        "act-006",
        "act-007",
        "act-008",
        "act-009",
        "act-010",
        "act-011"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-002",
      "table_id": "table-001",
      "row_position": 5,
      "activity_name": "Informed consent",
      "activity_name_source": {
        "cell_text": "Informed consent",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-003",
      "table_id": "table-001",
      "row_position": 6,
      "activity_name": "Admit to unit",
      "activity_name_source": {
        "cell_text": "Admit to unit",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-004",
      "table_id": "table-001",
      "row_position": 7,
      "activity_name": "Discharge from unit",
      "activity_name_source": {
        "cell_text": "Discharge from unitf",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "f",
      "linked_annotation_ids": [
        "annot-006"
      ]
    },
    {
      "activity_id": "act-005",
      "table_id": "table-001",
      "row_position": 8,
      "activity_name": "Outpatient visit or phone call",
      "activity_name_source": {
        "cell_text": "Outpatient visit or phone call",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-006",
      "table_id": "table-001",
      "row_position": 9,
      "activity_name": "Inclusion/exclusion",
      "activity_name_source": {
        "cell_text": "Inclusion/exclusion",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-007",
      "table_id": "table-001",
      "row_position": 10,
      "activity_name": "Discuss/document contraception",
      "activity_name_source": {
        "cell_text": "Discuss/document contraception",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-008",
      "table_id": "table-001",
      "row_position": 11,
      "activity_name": "Follicle-stimulating hormone (post-menopausal females only)",
      "activity_name_source": {
        "cell_text": "Follicle-stimulating hormone (post-menopausal females onlyh)",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "h",
      "linked_annotation_ids": [
        "annot-008"
      ]
    },
    {
      "activity_id": "act-009",
      "table_id": "table-001",
      "row_position": 12,
      "activity_name": "Alcohol test",
      "activity_name_source": {
        "cell_text": "Alcohol test",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-010",
      "table_id": "table-001",
      "row_position": 13,
      "activity_name": "Urine drug screen",
      "activity_name_source": {
        "cell_text": "Urine drug screen",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-011",
      "table_id": "table-001",
      "row_position": 14,
      "activity_name": "HIV, hepatitis B and C screen",
      "activity_name_source": {
        "cell_text": "HIV, hepatitis B and C screen",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-001",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-012",
      "table_id": "table-001",
      "row_position": 15,
      "activity_name": "Study Administration",
      "activity_name_source": {
        "cell_text": "Study Administration",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-013",
        "act-014",
        "act-015",
        "act-016",
        "act-017"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-013",
      "table_id": "table-001",
      "row_position": 16,
      "activity_name": "Medical history/demographics",
      "activity_name_source": {
        "cell_text": "Medical history/demographicsi",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-012",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "i",
      "linked_annotation_ids": [
        "annot-009"
      ]
    },
    {
      "activity_id": "act-014",
      "table_id": "table-001",
      "row_position": 17,
      "activity_name": "WD history",
      "activity_name_source": {
        "cell_text": "WD historyj",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-012",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "j",
      "linked_annotation_ids": [
        "annot-010"
      ]
    },
    {
      "activity_id": "act-015",
      "table_id": "table-001",
      "row_position": 18,
      "activity_name": "Prior WD treatment",
      "activity_name_source": {
        "cell_text": "Prior WD treatmentj",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-012",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "j",
      "linked_annotation_ids": [
        "annot-010"
      ]
    },
    {
      "activity_id": "act-016",
      "table_id": "table-001",
      "row_position": 19,
      "activity_name": "Physical examination",
      "activity_name_source": {
        "cell_text": "Physical examinationk",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-012",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "k",
      "linked_annotation_ids": [
        "annot-011"
      ]
    },
    {
      "activity_id": "act-017",
      "table_id": "table-001",
      "row_position": 20,
      "activity_name": "Height, weight, and BMI",
      "activity_name_source": {
        "cell_text": "Heightl, weight, and BMI",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-012",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "l",
      "linked_annotation_ids": [
        "annot-012"
      ]
    },
    {
      "activity_id": "act-018",
      "table_id": "table-001",
      "row_position": 21,
      "activity_name": "Enrollment",
      "activity_name_source": {
        "cell_text": "Enrollment",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-019",
        "act-020",
        "act-021"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-019",
      "table_id": "table-001",
      "row_position": 22,
      "activity_name": "Enrollment/inclusion",
      "activity_name_source": {
        "cell_text": "Enrollment/inclusion",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-018",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "table_id": "table-001",
      "row_position": 23,
      "activity_name": "Discontinue chelation therapy",
      "activity_name_source": {
        "cell_text": "Discontinue chelation therapy",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-018",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "table_id": "table-001",
      "row_position": 24,
      "activity_name": "Discontinue zinc therapy",
      "activity_name_source": {
        "cell_text": "Discontinue zinc therapy",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-018",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-022",
      "table_id": "table-001",
      "row_position": 25,
      "activity_name": "Administration of Study Intervention",
      "activity_name_source": {
        "cell_text": "Administration of Study Interventionm",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-023",
        "act-024",
        "act-025"
      ],
      "has_schedule_data": false,
      "annotation_markers": "m",
      "linked_annotation_ids": [
        "annot-013"
      ]
    },
    {
      "activity_id": "act-023",
      "table_id": "table-001",
      "row_position": 26,
      "activity_name": "ALXN1840 15 mg/day",
      "activity_name_source": {
        "cell_text": "ALXN1840 15 mg/day",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-022",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "table_id": "table-001",
      "row_position": 27,
      "activity_name": "ALXN1840 30 mg/day",
      "activity_name_source": {
        "cell_text": "ALXN1840 30 mg/day",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-022",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-025",
      "table_id": "table-001",
      "row_position": 28,
      "activity_name": "Study intervention compliance",
      "activity_name_source": {
        "cell_text": "Study intervention compliance",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-022",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-026",
      "table_id": "table-001",
      "row_position": 29,
      "activity_name": "PK/PD Analyses",
      "activity_name_source": {
        "cell_text": "PK/PD Analyseso",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-027",
        "act-028"
      ],
      "has_schedule_data": false,
      "annotation_markers": "o",
      "linked_annotation_ids": [
        "annot-015"
      ]
    },
    {
      "activity_id": "act-027",
      "table_id": "table-001",
      "row_position": 30,
      "activity_name": "Blood sampling for PK: Plasma total Mo and PUF-Mo",
      "activity_name_source": {
        "cell_text": "Blood sampling for PK: Plasma total Mo and PUF-Mo",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-026",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-028",
      "table_id": "table-001",
      "row_position": 31,
      "activity_name": "PD: Plasma total and PUF-Cu, LBC, ceruloplasmin, ceruloplasmin-bound Cu",
      "activity_name_source": {
        "cell_text": "PD: Plasma total and PUF-Cu, LBC, ceruloplasmin, ceruloplasmin-bound Cu",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-026",
      "child_activity_ids": [],
      "has_schedule_data": false,
      "annotation_markers": "n1",
      "linked_annotation_ids": [
        "annot-025"
      ]
    },
    {
      "activity_id": "act-029",
      "table_id": "table-001",
      "row_position": 32,
      "activity_name": "Safety Assessments / Laboratory Analyses",
      "activity_name_source": {
        "cell_text": "Safety Assessments / Laboratory Analyses",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-030",
        "act-031",
        "act-032",
        "act-033",
        "act-034",
        "act-035",
        "act-036"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "table_id": "table-001",
      "row_position": 33,
      "activity_name": "Chemistry, hematology, Coagulation",
      "activity_name_source": {
        "cell_text": "Chemistryq, hematology, Coagulation",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "q",
      "linked_annotation_ids": [
        "annot-017"
      ]
    },
    {
      "activity_id": "act-031",
      "table_id": "table-001",
      "row_position": 34,
      "activity_name": "Urinalysis",
      "activity_name_source": {
        "cell_text": "Urinalysis",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-032",
      "table_id": "table-001",
      "row_position": 35,
      "activity_name": "Urine/serum pregnancy test",
      "activity_name_source": {
        "cell_text": "Urine/serum pregnancy tests",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "s",
      "linked_annotation_ids": [
        "annot-019"
      ]
    },
    {
      "activity_id": "act-033",
      "table_id": "table-001",
      "row_position": 36,
      "activity_name": "Retained serum sample (safety)",
      "activity_name_source": {
        "cell_text": "Retained serum sample (safety)t",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "t",
      "linked_annotation_ids": [
        "annot-020"
      ]
    },
    {
      "activity_id": "act-034",
      "table_id": "table-001",
      "row_position": 37,
      "activity_name": "Vitals sign measurements",
      "activity_name_source": {
        "cell_text": "Vitals sign measurementsu",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "u",
      "linked_annotation_ids": [
        "annot-021"
      ]
    },
    {
      "activity_id": "act-035",
      "table_id": "table-001",
      "row_position": 38,
      "activity_name": "12-lead ECG (triplicate)",
      "activity_name_source": {
        "cell_text": "12-lead ECG (triplicate)",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "table_id": "table-001",
      "row_position": 39,
      "activity_name": "Adverse events",
      "activity_name_source": {
        "cell_text": "Adverse events",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-029",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-037",
      "table_id": "table-001",
      "row_position": 40,
      "activity_name": "Balance assessments",
      "activity_name_source": {
        "cell_text": "Balance assessments",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-038",
        "act-039",
        "act-040",
        "act-041",
        "act-042"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "table_id": "table-001",
      "row_position": 41,
      "activity_name": "Cu/Mo-controlled meals",
      "activity_name_source": {
        "cell_text": "Cu/Mo-controlled mealsv",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-037",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "v",
      "linked_annotation_ids": [
        "annot-022"
      ]
    },
    {
      "activity_id": "act-039",
      "table_id": "table-001",
      "row_position": 42,
      "activity_name": "Light exercise regimen",
      "activity_name_source": {
        "cell_text": "Light exercise regimen",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-037",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "table_id": "table-001",
      "row_position": 43,
      "activity_name": "Urination and bowel movement monitoring, menstruation check",
      "activity_name_source": {
        "cell_text": "Urination and bowel movement monitoring, menstruation checks",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-037",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "s",
      "linked_annotation_ids": [
        "annot-019"
      ]
    },
    {
      "activity_id": "act-041",
      "table_id": "table-001",
      "row_position": 44,
      "activity_name": "24-hour urine for Cu and Mo",
      "activity_name_source": {
        "cell_text": "24-hour urine for Cu and Mow",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-037",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "w",
      "linked_annotation_ids": [
        "annot-023"
      ]
    },
    {
      "activity_id": "act-042",
      "table_id": "table-001",
      "row_position": 45,
      "activity_name": "Feces for Cu and Mo",
      "activity_name_source": {
        "cell_text": "Feces for Cu and Mox",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-037",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "x",
      "linked_annotation_ids": [
        "annot-024"
      ]
    },
    {
      "activity_id": "act-043",
      "table_id": "table-001",
      "row_position": 46,
      "activity_name": "Other",
      "activity_name_source": {
        "cell_text": "Other",
        "indentation_level": 0,
        "indentation_method": "font_signal",
        "text_formatting": [
          "bold"
        ]
      },
      "hierarchy_level": 0,
      "is_section_header": true,
      "parent_activity_id": null,
      "child_activity_ids": [
        "act-044"
      ],
      "has_schedule_data": false,
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "table_id": "table-001",
      "row_position": 47,
      "activity_name": "Concomitant medication and non-pharmacologic therapy/procedure",
      "activity_name_source": {
        "cell_text": "Concomitant medication and non-pharmacologic therapy/procedure",
        "indentation_level": 1,
        "indentation_method": "font_signal"
      },
      "hierarchy_level": 1,
      "is_section_header": false,
      "parent_activity_id": "act-043",
      "child_activity_ids": [],
      "has_schedule_data": true,
      "annotation_markers": "",
      "linked_annotation_ids": []
    }
  ],
  "activity_schedule": [
    {
      "activity_id": "act-002",
      "column_id": "col-002",
      "row_position": 5,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-003",
      "column_id": "col-004",
      "row_position": 6,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-003",
      "column_id": "col-014",
      "row_position": 6,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-004",
      "column_id": "col-012",
      "row_position": 7,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-004",
      "column_id": "col-023",
      "row_position": 7,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-005",
      "column_id": "col-013",
      "row_position": 8,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "g",
      "linked_annotation_ids": [
        "annot-007"
      ]
    },
    {
      "activity_id": "act-006",
      "column_id": "col-002",
      "row_position": 9,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-006",
      "column_id": "col-004",
      "row_position": 9,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-006",
      "column_id": "col-008",
      "row_position": 9,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-007",
      "column_id": "col-002",
      "row_position": 10,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-007",
      "column_id": "col-004",
      "row_position": 10,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-007",
      "column_id": "col-012",
      "row_position": 10,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-007",
      "column_id": "col-025",
      "row_position": 10,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-008",
      "column_id": "col-002",
      "row_position": 11,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-009",
      "column_id": "col-002",
      "row_position": 12,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-009",
      "column_id": "col-004",
      "row_position": 12,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-010",
      "column_id": "col-002",
      "row_position": 13,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-010",
      "column_id": "col-004",
      "row_position": 13,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-011",
      "column_id": "col-002",
      "row_position": 14,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-013",
      "column_id": "col-002",
      "row_position": 16,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-014",
      "column_id": "col-002",
      "row_position": 17,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-015",
      "column_id": "col-002",
      "row_position": 18,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-015",
      "column_id": "col-008",
      "row_position": 18,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-016",
      "column_id": "col-002",
      "row_position": 19,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-016",
      "column_id": "col-004",
      "row_position": 19,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-016",
      "column_id": "col-014",
      "row_position": 19,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-016",
      "column_id": "col-025",
      "row_position": 19,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-017",
      "column_id": "col-002",
      "row_position": 20,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-017",
      "column_id": "col-004",
      "row_position": 20,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-017",
      "column_id": "col-014",
      "row_position": 20,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-017",
      "column_id": "col-023",
      "row_position": 20,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-019",
      "column_id": "col-005",
      "row_position": 22,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-007",
      "row_position": 23,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-008",
      "row_position": 23,
      "column_position": 8,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-009",
      "row_position": 23,
      "column_position": 9,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-010",
      "row_position": 23,
      "column_position": 10,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-011",
      "row_position": 23,
      "column_position": 11,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-012",
      "row_position": 23,
      "column_position": 12,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-013",
      "row_position": 23,
      "column_position": 13,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-014",
      "row_position": 23,
      "column_position": 14,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-015",
      "row_position": 23,
      "column_position": 15,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-016",
      "row_position": 23,
      "column_position": 16,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-017",
      "row_position": 23,
      "column_position": 17,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-018",
      "row_position": 23,
      "column_position": 18,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-019",
      "row_position": 23,
      "column_position": 19,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-020",
      "row_position": 23,
      "column_position": 20,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-021",
      "row_position": 23,
      "column_position": 21,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-022",
      "row_position": 23,
      "column_position": 22,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-023",
      "row_position": 23,
      "column_position": 23,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-024",
      "row_position": 23,
      "column_position": 24,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-020",
      "column_id": "col-025",
      "row_position": 23,
      "column_position": 25,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "8:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-003",
      "row_position": 24,
      "column_position": 3,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-004",
      "row_position": 24,
      "column_position": 4,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-005",
      "row_position": 24,
      "column_position": 5,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-006",
      "row_position": 24,
      "column_position": 6,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-007",
      "row_position": 24,
      "column_position": 7,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-008",
      "row_position": 24,
      "column_position": 8,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-009",
      "row_position": 24,
      "column_position": 9,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-010",
      "row_position": 24,
      "column_position": 10,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-011",
      "row_position": 24,
      "column_position": 11,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-012",
      "row_position": 24,
      "column_position": 12,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-013",
      "row_position": 24,
      "column_position": 13,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-014",
      "row_position": 24,
      "column_position": 14,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-015",
      "row_position": 24,
      "column_position": 15,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-016",
      "row_position": 24,
      "column_position": 16,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-017",
      "row_position": 24,
      "column_position": 17,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-018",
      "row_position": 24,
      "column_position": 18,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-019",
      "row_position": 24,
      "column_position": 19,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-020",
      "row_position": 24,
      "column_position": 20,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-021",
      "row_position": 24,
      "column_position": 21,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-022",
      "row_position": 24,
      "column_position": 22,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-023",
      "row_position": 24,
      "column_position": 23,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-024",
      "row_position": 24,
      "column_position": 24,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-021",
      "column_id": "col-025",
      "row_position": 24,
      "column_position": 25,
      "cell_value": "→",
      "cell_value_type": "continuation",
      "source_range": "4:25",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-008",
      "row_position": 26,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-009",
      "row_position": 26,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-010",
      "row_position": 26,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-011",
      "row_position": 26,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-012",
      "row_position": 26,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-013",
      "row_position": 26,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-014",
      "row_position": 26,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-015",
      "row_position": 26,
      "column_position": 15,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-016",
      "row_position": 26,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-023",
      "column_id": "col-017",
      "row_position": 26,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "column_id": "col-018",
      "row_position": 27,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "column_id": "col-019",
      "row_position": 27,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "column_id": "col-020",
      "row_position": 27,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "column_id": "col-021",
      "row_position": 27,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-024",
      "column_id": "col-022",
      "row_position": 27,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-025",
      "column_id": "col-013",
      "row_position": 28,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "n",
      "linked_annotation_ids": [
        "annot-014"
      ]
    },
    {
      "activity_id": "act-025",
      "column_id": "col-014",
      "row_position": 28,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-008",
      "row_position": 30,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "p",
      "linked_annotation_ids": [
        "annot-016"
      ]
    },
    {
      "activity_id": "act-027",
      "column_id": "col-010",
      "row_position": 30,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-016",
      "row_position": 30,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "p",
      "linked_annotation_ids": [
        "annot-016"
      ]
    },
    {
      "activity_id": "act-027",
      "column_id": "col-017",
      "row_position": 30,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-018",
      "row_position": 30,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "p",
      "linked_annotation_ids": [
        "annot-016"
      ]
    },
    {
      "activity_id": "act-027",
      "column_id": "col-019",
      "row_position": 30,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-020",
      "row_position": 30,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-021",
      "row_position": 30,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-027",
      "column_id": "col-022",
      "row_position": 30,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "p",
      "linked_annotation_ids": [
        "annot-016"
      ]
    },
    {
      "activity_id": "act-027",
      "column_id": "col-023",
      "row_position": 30,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-002",
      "row_position": 33,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-004",
      "row_position": 33,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-007",
      "row_position": 33,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "r",
      "linked_annotation_ids": [
        "annot-018"
      ]
    },
    {
      "activity_id": "act-030",
      "column_id": "col-011",
      "row_position": 33,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-013",
      "row_position": 33,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "g",
      "linked_annotation_ids": [
        "annot-007"
      ]
    },
    {
      "activity_id": "act-030",
      "column_id": "col-014",
      "row_position": 33,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-017",
      "row_position": 33,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "r",
      "linked_annotation_ids": [
        "annot-018"
      ]
    },
    {
      "activity_id": "act-030",
      "column_id": "col-019",
      "row_position": 33,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-023",
      "row_position": 33,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-030",
      "column_id": "col-025",
      "row_position": 33,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-002",
      "row_position": 34,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-004",
      "row_position": 34,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-011",
      "row_position": 34,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-013",
      "row_position": 34,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "g",
      "linked_annotation_ids": [
        "annot-007"
      ]
    },
    {
      "activity_id": "act-031",
      "column_id": "col-014",
      "row_position": 34,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-017",
      "row_position": 34,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-023",
      "row_position": 34,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-031",
      "column_id": "col-025",
      "row_position": 34,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-032",
      "column_id": "col-002",
      "row_position": 35,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-032",
      "column_id": "col-004",
      "row_position": 35,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-032",
      "column_id": "col-014",
      "row_position": 35,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-032",
      "column_id": "col-025",
      "row_position": 35,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-033",
      "column_id": "col-005",
      "row_position": 36,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-002",
      "row_position": 37,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-005",
      "row_position": 37,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-008",
      "row_position": 37,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-012",
      "row_position": 37,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-014",
      "row_position": 37,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-023",
      "row_position": 37,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-034",
      "column_id": "col-025",
      "row_position": 37,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-002",
      "row_position": 38,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-005",
      "row_position": 38,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-008",
      "row_position": 38,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-012",
      "row_position": 38,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-014",
      "row_position": 38,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-022",
      "row_position": 38,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-035",
      "column_id": "col-025",
      "row_position": 38,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-002",
      "row_position": 39,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-004",
      "row_position": 39,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-005",
      "row_position": 39,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-006",
      "row_position": 39,
      "column_position": 6,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-007",
      "row_position": 39,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-008",
      "row_position": 39,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-009",
      "row_position": 39,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-010",
      "row_position": 39,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-011",
      "row_position": 39,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-012",
      "row_position": 39,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-013",
      "row_position": 39,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-014",
      "row_position": 39,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-015",
      "row_position": 39,
      "column_position": 15,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-016",
      "row_position": 39,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-017",
      "row_position": 39,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-018",
      "row_position": 39,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-019",
      "row_position": 39,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-020",
      "row_position": 39,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-021",
      "row_position": 39,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-022",
      "row_position": 39,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-023",
      "row_position": 39,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-036",
      "column_id": "col-025",
      "row_position": 39,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-005",
      "row_position": 41,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-006",
      "row_position": 41,
      "column_position": 6,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-007",
      "row_position": 41,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-008",
      "row_position": 41,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-009",
      "row_position": 41,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-010",
      "row_position": 41,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-011",
      "row_position": 41,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-014",
      "row_position": 41,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-015",
      "row_position": 41,
      "column_position": 15,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-016",
      "row_position": 41,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-017",
      "row_position": 41,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-018",
      "row_position": 41,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-019",
      "row_position": 41,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-020",
      "row_position": 41,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-021",
      "row_position": 41,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-038",
      "column_id": "col-022",
      "row_position": 41,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-005",
      "row_position": 42,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-006",
      "row_position": 42,
      "column_position": 6,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-007",
      "row_position": 42,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-008",
      "row_position": 42,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-009",
      "row_position": 42,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-010",
      "row_position": 42,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-011",
      "row_position": 42,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-012",
      "row_position": 42,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-013",
      "row_position": 42,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-014",
      "row_position": 42,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-015",
      "row_position": 42,
      "column_position": 15,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-016",
      "row_position": 42,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-017",
      "row_position": 42,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-018",
      "row_position": 42,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-019",
      "row_position": 42,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-020",
      "row_position": 42,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-021",
      "row_position": 42,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-039",
      "column_id": "col-022",
      "row_position": 42,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-007",
      "row_position": 43,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-008",
      "row_position": 43,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-009",
      "row_position": 43,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-010",
      "row_position": 43,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-011",
      "row_position": 43,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-016",
      "row_position": 43,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-017",
      "row_position": 43,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-018",
      "row_position": 43,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-019",
      "row_position": 43,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-020",
      "row_position": 43,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-021",
      "row_position": 43,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-040",
      "column_id": "col-022",
      "row_position": 43,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-007",
      "row_position": 44,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-008",
      "row_position": 44,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-009",
      "row_position": 44,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-010",
      "row_position": 44,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-011",
      "row_position": 44,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-016",
      "row_position": 44,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-017",
      "row_position": 44,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-018",
      "row_position": 44,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-019",
      "row_position": 44,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-020",
      "row_position": 44,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-021",
      "row_position": 44,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-041",
      "column_id": "col-022",
      "row_position": 44,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-007",
      "row_position": 45,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-008",
      "row_position": 45,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-009",
      "row_position": 45,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-010",
      "row_position": 45,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-011",
      "row_position": 45,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-016",
      "row_position": 45,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-017",
      "row_position": 45,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-018",
      "row_position": 45,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-019",
      "row_position": 45,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-020",
      "row_position": 45,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-021",
      "row_position": 45,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-042",
      "column_id": "col-022",
      "row_position": 45,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-002",
      "row_position": 47,
      "column_position": 2,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-004",
      "row_position": 47,
      "column_position": 4,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-005",
      "row_position": 47,
      "column_position": 5,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-006",
      "row_position": 47,
      "column_position": 6,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-007",
      "row_position": 47,
      "column_position": 7,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-008",
      "row_position": 47,
      "column_position": 8,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-009",
      "row_position": 47,
      "column_position": 9,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-010",
      "row_position": 47,
      "column_position": 10,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-011",
      "row_position": 47,
      "column_position": 11,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-012",
      "row_position": 47,
      "column_position": 12,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-013",
      "row_position": 47,
      "column_position": 13,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-014",
      "row_position": 47,
      "column_position": 14,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-015",
      "row_position": 47,
      "column_position": 15,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-016",
      "row_position": 47,
      "column_position": 16,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-017",
      "row_position": 47,
      "column_position": 17,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-018",
      "row_position": 47,
      "column_position": 18,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-019",
      "row_position": 47,
      "column_position": 19,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-020",
      "row_position": 47,
      "column_position": 20,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-021",
      "row_position": 47,
      "column_position": 21,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-022",
      "row_position": 47,
      "column_position": 22,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-023",
      "row_position": 47,
      "column_position": 23,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    },
    {
      "activity_id": "act-044",
      "column_id": "col-025",
      "row_position": 47,
      "column_position": 25,
      "cell_value": "X",
      "cell_value_type": "marker",
      "source_range": "",
      "annotation_markers": "",
      "linked_annotation_ids": []
    }
  ],
  "annotations": [
    {
      "annotation_id": "annot-001",
      "table_id": "table-001",
      "annotation_marker": "a",
      "annotation_type": "footnote",
      "annotation_text": "Within 42 days of ALXN1840 administration. Details of procedures that may be performed by sites designated as “screening sites” (only in the US) are detailed in Section 8.",
      "annotation_scope": "column",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [
          "col-002",
          "col-003"
        ],
        "activity_ids": [],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 1,
          "column_position": 2
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 1,
          "column_position": 3
        }
      ],
      "document_references": [
        {
          "kind": "section",
          "target": "8"
        }
      ]
    },
    {
      "annotation_id": "annot-002",
      "table_id": "table-001",
      "annotation_marker": "b",
      "annotation_type": "footnote",
      "annotation_text": "Participants will be admitted to the clinical research unit (CRU) at least 10 hours prior to enrollment and initiation of copper- and molybdenum-controlled diet.",
      "annotation_scope": "column",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [
          "col-004"
        ],
        "activity_ids": [],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 1,
          "column_position": 4
        }
      ]
    },
    {
      "annotation_id": "annot-003",
      "table_id": "table-001",
      "annotation_marker": "c",
      "annotation_type": "footnote",
      "annotation_text": "At the CRU’s discretion, participants may remain in the CRU or be readmitted on Day 22 with all procedures starting on Day 23.",
      "annotation_scope": "column",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [
          "col-013"
        ],
        "activity_ids": [],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 2,
          "column_position": 13
        }
      ]
    },
    {
      "annotation_id": "annot-004",
      "table_id": "table-001",
      "annotation_marker": "d",
      "annotation_type": "footnote",
      "annotation_text": "Unscheduled study visits may occur at any time during the study and may include any study procedure as deemed necessary by the Investigator.",
      "annotation_scope": "column",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [
          "col-024"
        ],
        "activity_ids": [],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 1,
          "column_position": 24
        }
      ]
    },
    {
      "annotation_id": "annot-005",
      "table_id": "table-001",
      "annotation_marker": "e",
      "annotation_type": "footnote",
      "annotation_text": "Participants are required to return to the CRU Day 54+/-2; participants will be discontinued from ALXN1840 medication by their physician at the latest by the Day 54 follow-up.",
      "annotation_scope": "column",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [
          "col-025"
        ],
        "activity_ids": [],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 1,
          "column_position": 25
        }
      ]
    },
    {
      "annotation_id": "annot-006",
      "table_id": "table-001",
      "annotation_marker": "f",
      "annotation_type": "footnote",
      "annotation_text": "Discharge from the unit may occur after completion of all procedures on Day 9 and on Day 40 and after the Investigator has reviewed all safety assessment (including safety laboratory tests) and confirmed that the participant is appropriate for discharge.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-004"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 7
        }
      ]
    },
    {
      "annotation_id": "annot-007",
      "table_id": "table-001",
      "annotation_marker": "g",
      "annotation_type": "footnote",
      "annotation_text": "A single outpatient visit or phone call and safety laboratory assessment should occur between Day 14 and Day 18. A phone call may take place on a different day than the blood draw within the Day 14 through Day 18 period.",
      "annotation_scope": "cell",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [],
        "cell_references": [
          {
            "activity_id": "act-005",
            "column_id": "col-013"
          },
          {
            "activity_id": "act-030",
            "column_id": "col-013"
          },
          {
            "activity_id": "act-031",
            "column_id": "col-013"
          }
        ]
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 8,
          "column_position": 13
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 33,
          "column_position": 13
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 34,
          "column_position": 13
        }
      ]
    },
    {
      "annotation_id": "annot-008",
      "table_id": "table-001",
      "annotation_marker": "h",
      "annotation_type": "footnote",
      "annotation_text": "If needed to confirm menopause.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-008"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 11
        }
      ]
    },
    {
      "annotation_id": "annot-009",
      "table_id": "table-001",
      "annotation_marker": "i",
      "annotation_type": "footnote",
      "annotation_text": "Parameters include age and sex. Race and ethnicity will be collected where permitted by local regulations.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-013"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 16
        }
      ]
    },
    {
      "annotation_id": "annot-010",
      "table_id": "table-001",
      "annotation_marker": "j",
      "annotation_type": "footnote",
      "annotation_text": "Wilson disease history will include diagnosis date, method of diagnosis, history of cirrhosis, details of any previous liver biopsies performed, and treatment received.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-014",
          "act-015"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 17
        },
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 18
        }
      ]
    },
    {
      "annotation_id": "annot-011",
      "table_id": "table-001",
      "annotation_marker": "k",
      "annotation_type": "footnote",
      "annotation_text": "A full physical examination will be performed at Screening, at check-in for the study, and at the End of the study/Early Termination Visit. A physical examination should also be performed on any participants with ongoing adverse events prior to discharge from the unit. Otherwise, a symptom-driven physical examination may be performed at other times, at the Principal Investigator’s discretion.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-016"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 19
        }
      ]
    },
    {
      "annotation_id": "annot-012",
      "table_id": "table-001",
      "annotation_marker": "l",
      "annotation_type": "footnote",
      "annotation_text": "Height at screening only.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-017"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 20
        }
      ]
    },
    {
      "annotation_id": "annot-013",
      "table_id": "table-001",
      "annotation_marker": "m",
      "annotation_type": "footnote",
      "annotation_text": "While in the CRU, study intervention will be administered after an overnight fast (ie, at least 10 hours) at the same time every morning; drug is to be administered with 240 mL of water and meals should be delayed a minimum of 2 hours after dosing. As an outpatient, participants are expected to take ALXN1840 at approximately the same time daily (+/-1 hour). Participants should take the medication with a glass of water on an empty stomach; meals should be delayed a minimum of 2 hours after dosing.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-022"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 25
        }
      ]
    },
    {
      "annotation_id": "annot-014",
      "table_id": "table-001",
      "annotation_marker": "n",
      "annotation_type": "footnote",
      "annotation_text": "During the outpatient period, participants will use SMS text messaging to confirm study intervention administration.",
      "annotation_scope": "cell",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [],
        "cell_references": [
          {
            "activity_id": "act-025",
            "column_id": "col-013"
          }
        ]
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 28,
          "column_position": 13
        }
      ]
    },
    {
      "annotation_id": "annot-015",
      "table_id": "table-001",
      "annotation_marker": "o",
      "annotation_type": "footnote",
      "annotation_text": "Blood sampling for PK/PD will occur before ALXN1840 administration and represents a predose trough. See Table 2 for PK/PD sampling on Days 1, 25, 29, and 39.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-026"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 29
        }
      ],
      "document_references": [
        {
          "kind": "table",
          "target": "2"
        }
      ]
    },
    {
      "annotation_id": "annot-016",
      "table_id": "table-001",
      "annotation_marker": "p",
      "annotation_type": "footnote",
      "annotation_text": "PK/PD collection will include timepoints described in the schedule of PK/PD assessment for Days 1, 25, 29, and 39 (Table 2).",
      "annotation_scope": "cell",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [],
        "cell_references": [
          {
            "activity_id": "act-027",
            "column_id": "col-008"
          },
          {
            "activity_id": "act-027",
            "column_id": "col-016"
          },
          {
            "activity_id": "act-027",
            "column_id": "col-018"
          },
          {
            "activity_id": "act-027",
            "column_id": "col-022"
          }
        ]
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 30,
          "column_position": 8
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 30,
          "column_position": 16
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 30,
          "column_position": 18
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 30,
          "column_position": 22
        }
      ],
      "document_references": [
        {
          "kind": "table",
          "target": "2"
        }
      ]
    },
    {
      "annotation_id": "annot-017",
      "table_id": "table-001",
      "annotation_marker": "q",
      "annotation_type": "footnote",
      "annotation_text": "Samples for serum chemistry will be obtained following a fast of at least 8 hours at the Screening Visit and at check-in. In case of rechecks, and postdose serum chemistry, participants may not have fasted for 6 or 8 hours before the serum chemistry sample is taken.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-030"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 33
        }
      ]
    },
    {
      "annotation_id": "annot-018",
      "table_id": "table-001",
      "annotation_marker": "r",
      "annotation_type": "footnote",
      "annotation_text": "Laboratory assessment including chemistry, hematology, and coagulation parameters should be performed on Days -8, -1, 8, 23, and 28 only.",
      "annotation_scope": "cell",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [],
        "cell_references": [
          {
            "activity_id": "act-030",
            "column_id": "col-007"
          },
          {
            "activity_id": "act-030",
            "column_id": "col-017"
          }
        ]
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 33,
          "column_position": 7
        },
        {
          "table_number": 1,
          "location_type": "schedule_cell",
          "row_position": 33,
          "column_position": 17
        }
      ]
    },
    {
      "annotation_id": "annot-019",
      "table_id": "table-001",
      "annotation_marker": "s",
      "annotation_type": "footnote",
      "annotation_text": "Menstruation check is for women only; women of childbearing potential should only be enrolled after a negative serum pregnancy test result at Screening. Additional urine pregnancy testing will be standard for the protocol unless serum testing is required by site policies, local regulation, or Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs) (Section 10.2). In addition to pregnancy tests detailed at the visits in the SoA, females of childbearing potential will be required to perform urine pregnancy tests at least every 4 weeks at their home or the study site throughout their time in the study.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-032",
          "act-040"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 35
        },
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 43
        }
      ],
      "document_references": [
        {
          "kind": "section",
          "target": "10.2"
        }
      ]
    },
    {
      "annotation_id": "annot-020",
      "table_id": "table-001",
      "annotation_marker": "t",
      "annotation_type": "footnote",
      "annotation_text": "A single 15 mL serum sample will be retained for evaluation in the event of an unexpected safety finding; retained samples may be destroyed after completion of the clinical study report.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-033"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 36
        }
      ]
    },
    {
      "annotation_id": "annot-021",
      "table_id": "table-001",
      "annotation_marker": "u",
      "annotation_type": "footnote",
      "annotation_text": "Vital signs measurements and ECGs should be performed predose, unless otherwise specified. Vitals signs include body temperature, heart rate, respiratory rate, and systolic and diastolic blood pressure.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-034"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 37
        }
      ]
    },
    {
      "annotation_id": "annot-022",
      "table_id": "table-001",
      "annotation_marker": "v",
      "annotation_type": "footnote",
      "annotation_text": "Copper- and molybdenum-controlled diet will be initiated after registration/inclusion. Participants will remain on a copper/molybdenum controlled diet throughout both the inpatient Period 1 (Day -8 to Day 9) and inpatient Period 2 (Day 23 to Day 40); during this time participants will be strongly encouraged to complete all meals. While not in the CRU, participants will be encouraged to adhere to their usual copper-controlled diet.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-038"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 41
        }
      ]
    },
    {
      "annotation_id": "annot-023",
      "table_id": "table-001",
      "annotation_marker": "w",
      "annotation_type": "footnote",
      "annotation_text": "For each input/output balance period, 24-hour urine samples are to be collected for measurement of copper and molybdenum.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-041"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 44
        }
      ]
    },
    {
      "annotation_id": "annot-024",
      "table_id": "table-001",
      "annotation_marker": "x",
      "annotation_type": "footnote",
      "annotation_text": "For fecal samples, each individual sample will be independently collected with record of date, time, and weight of the sample.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-042"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 45
        }
      ]
    },
    {
      "annotation_id": "annot-025",
      "table_id": "table-001",
      "annotation_marker": "n1",
      "annotation_type": "footnote",
      "annotation_text": "Reviewer note, not source content: this row prints with no marks at the top of page 15. Table 2 (page 17) prints 'Blood sampling for PK: Plasma total Mo and PUF-Mo' and 'PD: Plasma total and PUF-Cu, LBC, ceruloplasmin, ceruloplasmin-bound Cu' in one cell with one set of marks, so this row is probably the continuation of the PK row above (row 30, page 14), split by the page break. Not asserted: Table 2 covers only Days 1, 25, 29 and 39, so the PD sampling days are not stated for Table 1.",
      "annotation_scope": "activity",
      "referenced_elements": {
        "property_ids": [],
        "column_ids": [],
        "activity_ids": [
          "act-028"
        ],
        "cell_references": []
      },
      "marker_locations": [
        {
          "table_number": 1,
          "location_type": "activity_name",
          "row_position": 31,
          "method": "synthesized"
        }
      ]
    }
  ],
  "review_items": [
    {
      "id": "D1",
      "severity": "medium",
      "location": {
        "page": 14,
        "row_positions": [
          1,
          2
        ]
      },
      "call_made": "The top header band (Screening / C-I / UNS / EOS or ET) is typed as the study phase (epoch, level 1) and the second band (Inpatient Period 1 / OP / Inpatient Period 2) as sub-periods (period, level 2); both names are synthesised because the label cell only reads 'Study Procedures'.",
      "alternative": "Type the top band as visit categories (visit) — Screening, Check-in, Unscheduled and EOS/ET read as visit names — and keep the second band as epoch.",
      "report_section": "2.2"
    },
    {
      "id": "D2",
      "severity": "high",
      "location": {
        "page": 14,
        "row_positions": [
          23,
          24
        ]
      },
      "call_made": "The arrows after the X in 'Discontinue chelation therapy' (X at Day -4 through -1) and 'Discontinue zinc therapy' (X at Day -21) are distributed as '→' over every following column through the EOS column (8:25 and 4:25), including the UNS column, because the drawn arrowhead ends inside the EOS column.",
      "alternative": "Stop the arrow span at Day 40 (column 23), treating the arrowhead overshoot into UNS/EOS as drawing slack, or keep only the X and treat the arrow as 'discontinued for the rest of the study' without per-column entries.",
      "report_section": "2.3"
    },
    {
      "id": "D3",
      "severity": "high",
      "location": {
        "page": 15,
        "row_position": 31
      },
      "call_made": "'PD: Plasma total and PUF-Cu, LBC, ceruloplasmin, ceruloplasmin-bound Cu' (first row on page 15) is transcribed with no marks, exactly as printed.",
      "alternative": "Treat it as the second half of the PK blood-sampling row split by the page break (Table 2 prints PK and PD in one cell sharing marks) and copy the PK row's marks (Days 1, 4-7, 25, 26-28, 29, 30-35, 36, 37-38, 39, 40, with footnote p at Days 1, 25, 29, 39) onto the PD row.",
      "report_section": "2.4"
    }
  ]
}