{ "schema_name": "soa-table-resolved", "schema_version": "1.2", "resolution_metadata": { "resolved_at": "2026-10-03T15:51:09.980587+00:00", "resolver": "soa2usdm.steps.resolve v1.0", "source_extraction": { "schema_name": "soa-table-extraction", "schema_version": "1.0", "extraction_file": "NCT05324124_Table_01_extraction.verified.json", "extraction_status": "ready_for_resolution" }, "validation_results": { "structure_valid": true, "hierarchy_valid": true, "annotations_valid": true, "validation_warnings": [ "Property 'Days' (type=other) has no hierarchical_level but sits between L1 and L2 — may be a missing level assignment" ], "validation_errors": [], "method_provenance": [ "activity_name:visual_transcription: 1", "annotation_text:deglyph_reconstruction: 1", "indentation_level:assumed_flat: 19", "marker_location:synthesized: 8", "property_structure:inferred_from_layout: 1", "schedule_cell:visual_read: 22" ] }, "resolution_status": "resolved_with_warnings", "ready_for_integration": true, "resolution_notes": "" }, "extraction_metadata": { "extracted_at": "2026-09-27T12:00:00Z", "extractor": "Claude, PDF_TO_JSON_PROMPT single-pass", "prompt_version": "3.8.1", "source_document": { "filename": "NCT05324124_soa.pdf", "document_type": "protocol" }, "extraction_status": "ready_for_resolution", "extraction_notes": "Single SoA table (section 1.3, protocol J2G-MC-JZPA) printed over document pages 9-12 with the header reprinted on every page; extracted as one table. Pages 9-11 are vector text-layer pages (marks verified by pdftotext -bbox column binning). Page 12 is a full-page raster with an invisible glyph-spread text layer; marks cross-checked by bbox, arrows read visually. A 'CCI' redaction box on page 12 may conceal activity rows. Label columns L=1 (Procedure); data columns 2-16; the right-hand Comments column (17) is a notes column rendered as footnote annotations with synthesized markers cm1-cm8. In-grid mark 'P' has no printed legend.", "model": "claude-opus-5-5" }, "table_metadata": { "table_id": "table-001", "table_number": 1, "table_type": "main_soa", "table_title": "Schedule of Activities (SoA)", "table_purpose": "Main study schedule: screening, 11-day inpatient treatment period, ED and follow-up phone call", "page_start": 9, "page_end": 12, "track_label": null, "column_count": 15, "row_count": 23, "header_row_count": 3, "activity_row_count": 20, "notes": "Only SoA table in the excerpt; primary anchor grid -> main_soa. The header reprints on pages 10-12 with identical columns and the rows continue; no separate table number or caption, so treated as one table spanning 9-12 (not a continuation)." }, "schedule_properties": [ { "property_id": "prop-001", "table_id": "table-001", "row_position": 1, "property_name": "Study period", "property_name_source": { "row_position": 1, "column_position": 1, "cell_value": "", "synthesized": true }, "property_type": "epoch", "property_comment": "Top header band naming study phases: Screening (col 2), Treatment Period (merged across cols 3-15, Day -1 to ED), Follow-Up phone call (col 16). Phase names -> epoch. Label cell empty; name synthesized.", "hierarchical_level": 1, "parent_property_id": null, "child_property_ids": [ "prop-003" ], "annotation_markers": "", "linked_annotation_ids": [] }, { "property_id": "prop-002", "table_id": "table-001", "row_position": 2, "property_name": "Days", "property_name_source": { "row_position": 2, "column_position": 1, "cell_value": "", "synthesized": true }, "property_type": "other", "property_comment": "Presentational band carrying the single spanning label 'Days' over cols 3-15, qualifying the numbers in row 3 as study days. It does not by itself distinguish any two columns, so hierarchical_level is null. Label cell empty; name taken from the spanning value.", "hierarchical_level": null, "parent_property_id": null, "child_property_ids": [], "annotation_markers": "", "linked_annotation_ids": [] }, { "property_id": "prop-003", "table_id": "table-001", "row_position": 3, "property_name": "Study day", "property_name_source": { "row_position": 3, "column_position": 1, "cell_value": "Procedure", "synthesized": true }, "property_type": "study_day", "property_comment": "Study-day row: '-28 to -2 days prior to Day 1' (Screening), Day -1, Days 1-11, ED (early discontinuation), and for the Follow-Up column the window 'within 7 to 10 days after last dose' (vertically merged across rows 2-3 in the source). Numeric day labels -> study_day. The printed label cell reads 'Procedure', which heads the activity column, so the property name is synthesized.", "hierarchical_level": 2, "parent_property_id": "prop-001", "child_property_ids": [], "annotation_markers": "", "linked_annotation_ids": [] } ], "schedule_columns": [ { "column_id": "col-002", "table_id": "table-001", "column_position": 2, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Screening", "is_merged": false, "annotation_markers": "" }, { "property_id": "prop-002", "value": "", "is_merged": false, "annotation_markers": "" }, { "property_id": "prop-003", "value": "-28 to -2 days prior to Day 1", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Screening / -28 to -2 days prior to Day 1", "linked_annotation_ids": [] }, { "column_id": "col-003", "table_id": "table-001", "column_position": 3, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "-1", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / -1", "linked_annotation_ids": [] }, { "column_id": "col-004", "table_id": "table-001", "column_position": 4, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "1", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 1", "linked_annotation_ids": [] }, { "column_id": "col-005", "table_id": "table-001", "column_position": 5, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "2", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 2", "linked_annotation_ids": [] }, { "column_id": "col-006", "table_id": "table-001", "column_position": 6, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "3", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 3", "linked_annotation_ids": [] }, { "column_id": "col-007", "table_id": "table-001", "column_position": 7, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "4", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 4", "linked_annotation_ids": [] }, { "column_id": "col-008", "table_id": "table-001", "column_position": 8, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "5", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 5", "linked_annotation_ids": [] }, { "column_id": "col-009", "table_id": "table-001", "column_position": 9, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "6", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 6", "linked_annotation_ids": [] }, { "column_id": "col-010", "table_id": "table-001", "column_position": 10, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "7", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 7", "linked_annotation_ids": [] }, { "column_id": "col-011", "table_id": "table-001", "column_position": 11, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "8", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 8", "linked_annotation_ids": [] }, { "column_id": "col-012", "table_id": "table-001", "column_position": 12, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "9", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 9", "linked_annotation_ids": [] }, { "column_id": "col-013", "table_id": "table-001", "column_position": 13, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "10", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 10", "linked_annotation_ids": [] }, { "column_id": "col-014", "table_id": "table-001", "column_position": 14, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "11", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / 11", "linked_annotation_ids": [] }, { "column_id": "col-015", "table_id": "table-001", "column_position": 15, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Treatment Period", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-002", "value": "Days", "is_merged": true, "annotation_markers": "" }, { "property_id": "prop-003", "value": "ED", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Treatment Period / Days / ED", "linked_annotation_ids": [] }, { "column_id": "col-016", "table_id": "table-001", "column_position": 16, "is_label_column": false, "column_values": [ { "property_id": "prop-001", "value": "Follow-Up phone call", "is_merged": false, "annotation_markers": "" }, { "property_id": "prop-002", "value": "", "is_merged": false, "annotation_markers": "" }, { "property_id": "prop-003", "value": "within 7 to 10 days after last dose", "is_merged": false, "annotation_markers": "" } ], "composite_label": "Follow-Up phone call / within 7 to 10 days after last dose", "linked_annotation_ids": [] } ], "activities": [ { "activity_id": "act-001", "table_id": "table-001", "row_position": 4, "activity_name": "Informed consent", "activity_name_source": { "cell_text": "Informed consent", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-002", "table_id": "table-001", "row_position": 5, "activity_name": "Inclusion and exclusion criteria", "activity_name_source": { "cell_text": "Inclusion and\nexclusion criteria", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-003", "table_id": "table-001", "row_position": 6, "activity_name": "Demography", "activity_name_source": { "cell_text": "Demography", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-004", "table_id": "table-001", "row_position": 7, "activity_name": "Participant admission to CRU", "activity_name_source": { "cell_text": "Participant\nadmission to CRU", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-005", "table_id": "table-001", "row_position": 8, "activity_name": "Participant discharge from CRU", "activity_name_source": { "cell_text": "Participant\ndischarge from\nCRU", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "cm1", "linked_annotation_ids": [ "annot-001" ] }, { "activity_id": "act-006", "table_id": "table-001", "row_position": 9, "activity_name": "Outpatient visit", "activity_name_source": { "cell_text": "Outpatient visit", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-007", "table_id": "table-001", "row_position": 10, "activity_name": "Medical history", "activity_name_source": { "cell_text": "Medical history", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-008", "table_id": "table-001", "row_position": 11, "activity_name": "Medical assessment", "activity_name_source": { "cell_text": "Medical\nassessment", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "cm2", "linked_annotation_ids": [ "annot-002" ] }, { "activity_id": "act-009", "table_id": "table-001", "row_position": 12, "activity_name": "Height and weight", "activity_name_source": { "cell_text": "Height and weight", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "cm3", "linked_annotation_ids": [ "annot-003" ] }, { "activity_id": "act-010", "table_id": "table-001", "row_position": 13, "activity_name": "Serum or urine pregnancy test (women of childbearing potential only)", "activity_name_source": { "cell_text": "Serum or urine\npregnancy test\n(women of\nchildbearing\npotential only)", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "cm4", "linked_annotation_ids": [ "annot-004" ] }, { "activity_id": "act-011", "table_id": "table-001", "row_position": 14, "activity_name": "Follicle-stimulating hormone (women of non-childbearing potential only)", "activity_name_source": { "cell_text": "Follicle-\nstimulating\nhormone (women\nof non-\nchildbearing\npotential only)", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-012", "table_id": "table-001", "row_position": 15, "activity_name": "Human immunodeficiency virus, hepatitis B and C screen", "activity_name_source": { "cell_text": "Human\nimmunodeficiency\nvirus, hepatitis B\nand C screen", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "", "linked_annotation_ids": [] }, { "activity_id": "act-013", "table_id": "table-001", "row_position": 16, "activity_name": "12-lead ECG", "activity_name_source": { "cell_text": "12-lead ECG", "indentation_level": 0, "indentation_method": "assumed_flat" }, "hierarchy_level": 0, "is_section_header": false, "parent_activity_id": null, "child_activity_ids": [], "has_schedule_data": true, "annotation_markers": "cm5", "linked_annotation_ids": [ "annot-005" ] }, { "activity_id": "act-014", "table_id": "table-001", "row_position": 17, "activity_name": "Vital signs (supine), pulse rate, and blood pressure", 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